Skin Treatment
PRP and PRP
with Exomine ERP
at AEOM
Regenerative treatments using your own blood — two options, two protocols
Platelet-Rich Plasma (PRP) and PRP with Exomine ERP are regenerative skin and hair treatments that use your own blood to stimulate collagen, support tissue repair and improve skin quality. We offer both — standard PRP as a course-based treatment for patients building a regenerative pathway, and PRP with Exomine ERP as a higher-concentration single-session alternative for patients wanting fewer visits and more pronounced regeneration.
Key facts strip:
- Standard PRP: Single session £450 • Course of 3 £1,200
- PRP with Exomine ERP: £995 (single session, every 6 months)
- Mild swelling for 24 hours • Minimal downtime
- Available for face, scalp (hair restoration), and combined regenerative work
From
£1,400
Downtime
None
Session
30–75 min
Areas
Face · Neck · Body
Results
12–18 months
Introduction
Two routes
into autologous regenerative care
PRP — Platelet-Rich Plasma — has been used in clinical medicine for over twenty years. The principle is straightforward: a small amount of your blood is drawn, processed to concentrate the platelets and the growth factors they contain, and re-introduced to the skin or scalp where it stimulates regenerative repair. Used properly, PRP is one of the most established, autologous regenerative treatments available — meaning the active component comes from your own body, which eliminates allergy or rejection risk.
At AEOM we offer two routes into PRP work:
Standard PRP — A course-based treatment, typically three sessions spaced 4–6 weeks apart, with maintenance every 6–12 months. The more accessible, more established protocol. Strong choice for patients building a regenerative skin pathway over time.
PRP with Exomine ERP — Our higher-concentration alternative. Uses the same blood draw but processes it through a specialist preparation system (an Advanced PRF tube and Microlyzer cutting tool) to release approximately 90–100 billion extracellular vesicles, of which around 98% are platelet-derived exosomes, according to the manufacturer's testing. A single session, typically delivering effects lasting around six months. The premium choice for patients wanting fewer visits or more pronounced regenerative work.
Both are autologous. Both are safe. They differ in concentration, preparation, frequency and cost — and we'll help you decide which is right for you at consultation.
HOW IT WORKS
The science, briefly
Standard PRP
Approximately 20ml of blood is drawn from your arm — similar to a routine blood test. The blood is then centrifuged (spun at high speed) to separate the platelets from other blood components. The platelet-rich layer is collected, prepared, and either injected into the treatment area or applied topically following microneedling.
Platelets carry growth factors — biological signalling molecules that direct tissue repair. When concentrated and re-introduced to the skin, they trigger a regenerative response: stimulating collagen synthesis, supporting new blood vessel formation, and accelerating cellular repair. The effect compounds across a course of sessions as repeated stimulation drives sustained collagen production.
PRP with Exomine ERP
The blood draw is the same, but the preparation is significantly more sophisticated. The PRP is processed through:
- A specialised Microlyzer cutting tool that applies controlled shear stress to the platelets, encouraging them to release their extracellular vesicles
- An Advanced PRF tube designed to further enhance vesicle release through its specific grooved structure
- A final centrifugation step that concentrates the released vesicles in the upper layer of the sample
The result, according to the manufacturer's lab analysis, is approximately 90–100 billion extracellular vesicles per treatment, of which around 98% are platelet-derived exosomes. The increased concentration of regenerative signalling means a single treatment typically delivers effects lasting around six months — rather than requiring a course.
The preparation process takes approximately 45 minutes in clinic, which is part of why the treatment carries a different price point.
WHO IT'S FOR
Who PRP work is right for
PRP and PRP with Exomine ERP are well-suited for patients dealing with:
Skin texture, fine lines and overall quality — particularly when combined with microneedling
Acne scarring — particularly atrophic and rolling scars
Post-weight-loss or GLP-1 skin laxity — combined with Sofwave for structural support
Hair thinning — for early-stage androgenic alopecia and post-pregnancy or stress-related shedding
Under-eye hollowing and tear trough quality — gentle regenerative work where filler would be too aggressive
Sun damage and pigmentation concerns
General skin regeneration — maintenance and prevention for patients investing in long-term skin health
Standard PRP is typically the better choice if:
You prefer a more accessible single-session price point
You're addressing skin quality progressively rather than seeking pronounced single-session change
You want to combine PRP with microneedling across a course
A pacemaker or implanted electronic device — typically not contraindicated but requires discussion
Pregnancy — Sofwave is not delivered during pregnancy
PRP with Exomine ERP is typically the better choice if:
You want fewer visits (one treatment vs three)
You're addressing significant scarring, deeper laxity, or post-weight-loss skin
You prefer a six-monthly maintenance cadence over a course-plus-maintenance approach
You're investing in flagship regenerative care (or considering the Regenerative Lift programme, which includes Exomine ERP)
Neither treatment is appropriate if you have:
Bleeding disorders or active blood-thinning medication (speak to us at consultation — risk profile shifts)
Active infections or open wounds in the treatment area
Active cancer or recent chemotherapy
Significant anaemia (we may run bloods first to confirm safety)
Pregnancy or breastfeeding — neither treatment is delivered during pregnancy
Keloid scarring history — we'd assess at consultation
WHAT TO EXPECT
Before, during and after
Before
Consultation & assessment
Every PRP patient begins with a consultation. We discuss your concerns, run a brief medical history review, and confirm which PRP route is right for you. For combined skin work, we typically include Observ 520x imaging.
Preparation (both treatments):
- Drink plenty of water in the 24 hours before treatment — hydration improves blood collection quality
- Avoid alcohol and caffeine for 24 hours before treatment
- Avoid blood-thinning supplements (high-dose Vitamin E, fish oil, garlic supplements) for 48 hours before, if comfortable to do so
- Do not take ibuprofen or aspirin for 48 hours before treatment unless medically necessary
- Come with clean skin, no makeup
During
Standard PRP
The treatment takes approximately 45 minutes per session:
- 0:00–0:10 — Blood drawn (approximately 20ml), centrifuged
- 0:10–0:20 — Numbing cream applied to the treatment area
- 0:20–0:40 — PRP injected into the face, scalp or combined with microneedling
- 0:40–0:45 — Aftercare, recovery advice
PRP with Exomine ERP
The treatment takes approximately 75 minutes due to the extended preparation:
- 0:00–0:10 — Blood drawn (approximately 20ml)
- 0:10–0:55 — Specialist preparation (45 minutes): processing through the Microlyzer and Advanced PRF tube, final centrifugation
- 0:25–0:35 — Numbing cream applied while preparation runs
- 0:55–1:10 — PRP with Exomine ERP injected into the treatment area
- 1:10–1:15 — Aftercare, recovery advice
After
both treatments
Immediately: Mild swelling, redness or small bumps at the injection sites — normal and expected. Skin may feel warm or tender. No bleeding visible.
24 hours: Swelling peaks. Slight bruising possible at injection sites. Skin may feel slightly tight. Most patients return to work the next day with light makeup if desired.
48–72 hours: Visible swelling settles. Mild tenderness may persist for 2–3 days. Skin starts to feel slightly fresher.
1–2 weeks: Skin clarity, hydration and texture typically improving. The regenerative work is now well underway.
4–6 weeks: Standard PRP — time for the next session in a course. Exomine ERP — full results becoming visible.
3 months: Both treatments — peak collagen response, visible texture and quality improvements at their clearest.
RESULTS
What results actually look like
PRP and PRP with Exomine ERP produce gradual rather than dramatic improvements — the regenerative work happens over weeks and months, not at the treatment table. Patients rarely describe immediate visible change; they describe their skin progressively looking healthier, more resilient and more balanced.
Specific changes most patients see:
- Improved skin texture and reduced roughness
- Smaller-appearing pores
- Visible improvement in acne scarring (typically 30–50% improvement after a full standard PRP course or a single Exomine ERP session)
- Reduced fine lines, particularly around the eyes
- More even skin tone
- Denser, more resilient skin
- Improved hair density and reduced shedding (for hair restoration applications)
Timeline:
Standard PRP (course of 3):
- Weeks 1–4: Subtle improvements from session 1
- Weeks 4–8: Compounding effects after session 2
- Weeks 8–12: Course completion; results building
- Month 3 post-completion: Peak results
- 6–12 months: Maintenance session recommended
PRP with Exomine ERP (single session):
- Weeks 1–4: Visible regenerative response building
- Weeks 4–12: Peak results
- 6 months: Results gradually decline; maintenance session recommended
PRP VS PRP WITH EXOMINE ERP — A PROPER COMPARISON
Choosing between the two
This is the most-asked question we get about PRP at AEOM, so we'll address it directly.
Comparison Point
Standard PRP
PRP with Exomine ERP
Preparation
Standard centrifuge separation
Microlyzer + Advanced PRF tube + final centrifugation (~45 mins)
Vesicle concentration
Standard platelet concentration
~90–100 billion vesicles per treatment, ~98% platelet-derived exosomes (per manufacturer's lab data)
Treatment protocol
Course of 3 sessions, 4–6 weeks apart
Single session, typically every 6 months
Treatment time per session
~45 minutes
~75 minutes
Maintenance frequency
Every 6–12 months after course
Every 6 months
Annual cost (approximate)
£1,200 course + maintenance (~£450) = £1,650 year one
£1,990 (two sessions per year)
Best for
Course-based regenerative pathway, accessible price point
Single-visit cadence, more pronounced regeneration
Combined with microneedling?
Yes, frequently
Less common — Exomine ERP typically injected directly
Combined with Sofwave (Regenerative Lift)?
Less commonly
Yes — the Regenerative Lift programme includes Exomine ERP specifically
The honest summary:
Standard PRP is the more established, more accessible protocol. For patients building a regenerative pathway and willing to commit to a course of three sessions, standard PRP delivers excellent value and excellent outcomes — and is the right choice for most patients exploring PRP for the first time.
PRP with Exomine ERP is a more premium, more concentrated protocol. The higher vesicle concentration typically means one session does the work of a course, with maintenance every six months rather than a course-plus-top-up rhythm. The price reflects the additional preparation time and consumable cost.
Neither is "better" — they suit different patients. We'll guide you at consultation based on your goals, your visit preferences and your budget.
PRP COMPARED WITH OTHER REGENERATIVE TREATMENTS
How PRP work
compares to alternatives
PRP vs Donor-Derived Exosomes
Some clinics offer "exosome" treatments using donor-derived material (typically from human placenta, stem cell sources or plant material). These are not autologous — they don't come from your own body. The regulatory landscape around donor-derived exosomes in the UK is evolving and currently restrictive; many products legally available in the US are not approved for injection in the UK. PRP and PRP with Exomine ERP are both autologous, derived from your own blood, with established safety profiles. We don't offer donor-derived injectable exosomes; the Exomine ERP route gives you the regenerative concentration without the safety or regulatory questions.
PRP vs Fillers
PRP doesn't add volume — it stimulates regeneration. Fillers add immediate volume but don't change underlying tissue quality. They address different concerns: PRP for skin quality, texture and regenerative work; fillers for structural volume. Patients sometimes do both, staged appropriately.
PRP vs Microneedling
Microneedling stimulates collagen through controlled micro-injury; PRP stimulates collagen through growth factor signalling. They're frequently combined — PRP applied topically following microneedling penetrates the channels created by the needling, amplifying the regenerative response. The combination is significantly more effective than either alone.
PRP vs Polynucleotides
Polynucleotide treatments (Plinest, Profhilo Skin, etc.) use synthetic regenerative biomaterials to stimulate tissue repair. They have a different mechanism, different evidence base, and a different price point. Polynucleotides are an emerging category we're tracking; for now, our regenerative pathway is built around the established evidence base of PRP and the higher-concentration Exomine ERP route.
PRICING
PRP and Exomine ERP pricing
Standard PRP
Treatment
Price
Duration
Single Treatment
£450
45 minutes
Course of 3
£1,200
45 minutes per session
Same-Day Add-On (alongside another treatment)
£300
+15 minutes
PRP with Exomine ERP
Treatment
Price
Duration
Single Session
£995
75 minutes (including 45-minute preparation)
Maintenance (every 6 months)
£995 per session
75 minutes per session
Klarna instalments available on standalone PRP treatments and Exomine ERP — typically up to 3 interest-free payments, subject to approval.
As part of a Programme:
- PRP with Exomine ERP is included in the AEOM Regenerative Lift programme alongside Sofwave Full Face & Neck, JetPeel, LED, IV nutrition and an aesthetic blood panel — £4,495 total.
- Standard PRP can be added to most other programmes or treatments at discounted pricing — we'll discuss at consultation.
COMBINE WITH
Treatments that combine well
with PRP
PRP + SkinPen Elite Microneedling
The most established combination. Standard PRP topically applied immediately after microneedling penetrates the micro-channels and amplifies the regenerative response. Recommended for patients addressing significant scarring or deeper texture work.
PRP with Exomine ERP + Sofwave
The combination delivered in our Regenerative Lift programme. Sofwave addresses structural collagen; Exomine ERP delivers regenerative tissue support. Particularly powerful for post-weight-loss skin laxity.
PRP + Skin Boosters (Profhilo)
PRP for regenerative quality; Profhilo for hydration and elasticity. Typically staged 2–3 weeks apart for compounding effect.
PRP + LED Therapy
LED applied after PRP sessions supports recovery and the regenerative response. Often included at no additional cost.
PRP + IV Nutrition
A Skin & Hair Glow IV around PRP treatment supports the regenerative work from within.
Frequently asked questions
What's the actual difference between standard PRP and PRP with Exomine ERP?
Both treatments use your own blood to support skin regeneration, but they work at different concentrations.
Standard PRP delivers platelets and the growth factors they contain — typically as a course of three to four sessions spaced 4–6 weeks apart, with maintenance every 6–12 months. PRP with Exomine ERP uses an additional preparation step — a Microlyzer cutting tool and an Advanced PRF tube — to release approximately 90–100 billion extracellular vesicles, of which around 98% are platelet-derived exosomes according to the manufacturer's testing. The higher vesicle concentration typically allows treatment as a single session, with maintenance every six months rather than a course. At consultation, we'll discuss which is right for you based on your goals, indication and preferred treatment frequency.
Is PRP painful?
Numbing cream applied before treatment significantly reduces discomfort.
The blood draw is similar to a routine blood test. The injections themselves feel like small pinches, with mild discomfort that settles quickly. Most patients describe the treatment as well-tolerated. The Exomine ERP version takes longer overall due to the preparation time but the actual injection portion is similar to standard PRP.
Is PRP safe?
Yes — PRP is one of the safest aesthetic treatments available because the active component comes from your own blood, eliminating allergy and rejection risk. The safety profile is well-established across decades of clinical use in medicine and aesthetics. Standard precautions apply: we don't deliver PRP to patients with bleeding disorders, active infections, certain medications, or during pregnancy.
How long does the blood draw take?
Approximately 5–10 minutes — similar to a routine blood test. We draw approximately 20ml of blood from a vein in your arm.
Will I bruise?
Mild bruising at injection sites is possible and typically settles within 5–7 days. Bruising risk is reduced by following pre-treatment advice (avoiding blood-thinning supplements and medications where possible). Significant bruising is uncommon.
Can PRP help with hair loss?
Yes — PRP for hair restoration is one of the most established applications. PRP injected into the scalp can support hair follicle health, reduce shedding, and stimulate new growth — particularly effective for early-stage androgenic alopecia and post-pregnancy or stress-related hair thinning. For hair restoration, we typically recommend a course of three sessions, spaced 4–6 weeks apart, with maintenance every 4–6 months. We'd discuss whether standard PRP or Exomine ERP is the better choice based on your specific concerns.
Can I have PRP if I'm taking blood thinners?
Speak to us at consultation. PRP relies on platelet function, which is affected by blood-thinning medications (warfarin, apixaban, daily aspirin, etc.). Depending on the medication and dosing, PRP may or may not be appropriate — and we may recommend a different treatment route. Don't stop prescribed medication without your doctor's guidance.
How does AEOM's PRP differ from cheaper PRP services elsewhere?
The variation in PRP quality across clinics is meaningful — and underappreciated.
Key factors include: the centrifuge used (clinical-grade vs basic), the preparation protocol (single-spin vs double-spin), the quality of the collection system (sealed vs open), and the experience of the practitioner. We use clinical-grade equipment, validated protocols, and treatments are delivered by our specialist nursing team. PRP at a discount price typically reflects compromises somewhere in this chain.
Why is PRP with Exomine ERP more expensive than standard PRP?
The Exomine ERP preparation requires specialist single-use kit (the Microlyzer and Advanced PRF tube), takes 45 minutes of additional in-clinic preparation time, and produces a meaningfully higher concentration of regenerative vesicles per treatment.
The price reflects the additional consumable cost and clinical time. Calculated annually, the difference between the two routes is moderate — Exomine ERP at £1,990/year (two sessions) vs standard PRP at ~£1,650/year (course + maintenance) — but the visit pattern and per-session experience differ significantly.
Is there a difference for hair vs face treatment?
The blood draw and preparation are identical. The injection technique differs: scalp injections are delivered into the dermal layer using fine needles in a structured pattern across the affected area; facial PRP can be delivered either by injection or topically following microneedling. We'd discuss the right approach at consultation.
Can I combine PRP with anti-wrinkle injections (Botox) or fillers?
Yes, with appropriate spacing. We'd typically deliver anti-wrinkle injections at a separate appointment, spaced 2 weeks before or after PRP. Combining with fillers requires more careful planning — speak to us at consultation.
Where is AEOM located?
Our clinic is at 116 Seymour Place in Marylebone, London.
Marylebone, Baker Street and Edgware Road stations are all under ten minutes on foot. Free street parking is available after 6.30pm, with paid bays on York Street nearby — daytime parking is reimbursed for treatments over £200. Treatments are by appointment only.
Ready to discuss PRP?
Both PRP routes are well-established and well-evidenced — but the right choice between them depends on your specific concerns, goals and visit preferences. Book a consultation and we'll discuss which protocol is most appropriate for you, and how it fits into your broader skin or hair plan.